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12-Day Rome, Florence, Venice, Milan Italy Tour with Siena, San Gimignano, Pisa, Verona

This tour of Italy’s Highlights combines Italy’s beautiful cities Rome, Florence, Venice and Milan with Italy’s charming Tuscan towns Pisa, San Gimignano, Siena plus northern Italy’s sophisticated town Verona. On this escorted trip through Italy, you’ll travel north from Rome through Tuscany, the Veneto, and finally to Milan. Along the way, you’ll explore central and northern Italy. The slow-paced tour itinerary includes 3-nights in Rome and Florence. This gives you time to unwind and stroll around these Italian cities. The tour itinerary includes visits to UNESCO world heritage sites including Vatican City, the historic centers of Rome, Florence, Venice, Pisa, San Gimignano, and Siena. For more information click here to review the daily itinerary below. For the price of the Rome, Florence, Venice Milan Italy tour with airfare from your preferred city submit the form or call 800.227.1577.


Rome, Florence, Venice, Milan Italy Tour with Siena, San Gimignano, Pisa, Verona Itinerary Highlights

  • ROME A special welcome dinner at a local restaurant; guided sightseeing, visit the Vatican Museums and Sistine Chapel, St. Peter’s Square and Basilica, and the Colosseum
  • SIENA – Walking tour including Piazza del Campo
  • SAN GIMIGNANO – Orientation
  • FLORENCE – Guided walking tour, visit Michelangelo’s David and Signoria Square, and Santa Croce Basilica
  • PISA – Marvel at the legendary Leaning Tower
  • VERRAZZANO CASTLE – Globus Local Favorite Wine tasting and lunch
  • BURANO – Lagoon cruise and island visit
  • VENICE – Private boat ride; guided walking tour, visit St. Mark’s Square and Basilica, Doges’ Palace and the Bridge of Sighs; glassblower demonstration
  • VERONA – Walking tour including Juliet’s balcony and the Arena
  • MILAN – Walking tour, visit the La Scala Opera House museum and the Galleria; farewell dinner at a local restaurant

Rome, Florence, Venice, Milan Italy Tour Inclusions

  • 9-nights first class accommodations.
  • Airport Transfers. Arrival and departure transfer when vacation is booked with airfare.
  • Meals: Breakfast daily, 1 lunch, and 2 dinners.
  • Wireless Headsets to hear your guide clearly and distinctly in public places.
  • Free Wifi on the motor coach
  • Baggage Handling. Never touch your bag! (except at airports)
  • Hotel Taxes, Hotel Service Charges and All Tips for hotel and restaurant personnel.
  • Professional Tour Directors travels with the group from beginning to end of the tour; licensed local destination-specific guides.


Rome 3 Nights – Mediterraneo Hotel

Florence 3 Nights – Starhotel Michelangelo

Venice, Murano 2 Nights – MGallery LGare Hotel

Milan 2 Nights – Starhotel Ritz

Click here to review the daily itinerary below.

Optional Tours


Join your Local Guide for a tailor-made itinerary featuring some of the city’s authentic jewels. A life-time experience!


Enjoy an unforgettable drive through the “Eternal City” followed by a 4-course dinner at a popular Roman restaurant.


Enjoy a guided visit to the famed Renaissance-era Villa d’Este.


An evening you’ll never forget. Find out first-hand that the best and the most delicate food and wines originate in Tuscany. Be sure to come with an appetite!


Enjoy a wonderful dinner with regional dishes prepared using the finest local ingredients.

Admire the world’s greatest collection of Italian and Florentine art.


Experience an unforgettable evening in Venice.


Enjoy a ride in a traditional gondola, gliding through centuries-old canals, under famous arched bridges, past lavish palaces and quaint piazzas.

Click here to review the daily itinerary below.

To book your Rome, Florence, Venice, Milan Italy tour with Siena, San Gimignano, Pisa, and Verona Italy Tour Submit form

Rome, Florence Venice, Milan Italy Tour Daily Itinerary

DAY 1 – Depart for Rome

Board your overnight flight to Rome, Italy.

DAY 2 Arrive in Rome, Italy

Welcome to Rome! At 5 pm, meet your Tour Director and traveling companions, and enjoy a special welcome dinner with wine at the rooftop restaurant of your hotel overlooking Rome.

Meals: Dinner

DAY 3 Rome

Today you’ll visit the Vatican Museum and Sistine Chapel. The Vatican Museum is full of treasure spanning from the ancient Egyptians, through the Etruscan civilization, to Ancient Rome and through the Renaissance and Baroque period to its contemporary art collection. After you’ll visit St. Peter’s Basilica to see Michelangelo’s Pietà and Berinis various sculptures. After you’ll travel outside Rome to the Castelli Romani to visit the Pope’s summer residence Castel Gondolfo and the gardens.

Meals: Breakfast

DAY 4 Rome

This morning, you’ll visit the St. Peter in Chains Basilica (San Pietro in Vincoli) where you’ll see Michelangelo’s famous Moses. After the tour continues to the Colosseum and Roman Forum. This afternoon you have time to stroll around Rome or you may join an optional tour of Rome.

Meals: Breakfast

DAY 5 Rome – Pisa – Florence

Today you’ll depart Rome to visit the famous Renaissance city Florence. Along the way you’ll enjoy an included excursion to Pisa. There marvel at the Field of Miracles, the lovely square where the Pisa Duomo, Baptistry, and Bell Tower are located. The Pisa Bell Tower is known as the Leaning Tower of Pisa. The entire piazza is a work of architectural mastery.

Meals: Breakfast

DAY 6 Florence excursion to Siena and San Gimignano

In Siena, enter the impressive medieval walls and walk through ancient, narrow lanes to Piazza del Campo, site of the biannual Palio, Siena’s spectacular medieval-style horse race. Then, continue through unforgettable landscapes of gently rolling, vine-clad hills to hilltop San Gimignano, and walk through the most picturesque of Italy’s perfectly preserved medieval towns. You’ll also enjoy a Chianti wine tasting in Tuscany’s hills.

Meals: Breakfast & Dinner

DAY 7 Florence.

During your walking tour with a Local Guide, visit the ACADEMY OF FINE ARTS to see Michelangelo’s celebrated David. Admire the magnificent cathedral, Giotto’s Bell Tower, the Baptistry’s heavy bronze “Gate of Paradise,” sculpture-studded SIGNORIA SQUARE, and visit SANTA CROCE BASILICA with the tomb of Michelangelo. The afternoon is free to shop for Florentine leather goods and gold jewelry sold by the ounce, which are attractive buys. And tonight is your chance to  go out in Florence on your own. Enjoy the culinary delights of a fine Tuscan restaurant.

Meals: Breakfast

DAY 8 Florence–Venice Island. Excursion to Burano

A spectacular drive through the wooded Apennine Mountains brings you to Venice, a powerful magnet for romantics and art lovers from around the globe. Join an unforgettable Venetian LAGOON CRUISE to the picturesque fishing village of Burano, renowned for its bright pastel-colored houses and for its lace making. Take pictures of traditional fishing boats, still used by the island inhabitants. Tonight, you may wish to try out local specialties in one of Venice’s excellent restaurants.

Meals: Breakfast

DAY 9 Venice Island

Enter in style by PRIVATE BOAT to ST. MARK’S SQUARE. Meet your Local Guide for a walking tour including visits to the byzantine ST. MARK’S BASILICA, lavish DOGES’ PALACE and the BRIDGE OF SIGHS. Also watch a skilled GLASSBLOWER fashion delicate objects in an age-old traditional manner. An optional gondola ride is available.

Meals: Breakfast

DAY 10 Venice Island–Verona–Milan

In Verona, the medieval setting of Shakespeare’s Romeo and Juliet, take pictures of Juliet’s balcony and rub the shining breast on her statue for good luck. Next, admire the Arena, an incredibly well-preserved pink marble Roman amphitheater, where gladiators once fought. Built in the 1st century AD, it is now the magical venue for world-famous opera performances. Then, on to the dynamic city of Milan, hub of Italy’s economic miracle.

Meals: Breakfast

Day 11 Milan

Your guided walking tour starts with a visit to the SFORZESCO CASTLE GROUNDS and MUSEUM. Also admire the glass-domed GALLERIA, the famous Scala Opera House, and the magnificent gothic Duomo. Afternoon at leisure to explore Milan’s famous shopping streets at your own pace and tonight, a farewell dinner has been prepared at one of Milan’s fine restaurants as a proper way to say arrivederci, Italia!

Meals: Breakfast & Dinner

DAY 12 Milan

Your vacation ends with breakfast this morning.

Click here Rome, Florence, Venice, Milan Italy tour highlights and itinerary map.

Submit form or call us today 800-227-1577 to book your Rome, Florence, Venice, Milan Italy tour package.

* When all-inclusive Italy vacation prices are quoted to include airfare the price includes fuel surcharges, airport taxes, Italy airport transfers and fees. All prices are per person based on twin occupancy. Italy tours with air & land tour prices apply from the gateway airport. Prices will vary from alternative gateway airports or cities and may be higher. The total price will be emailed to you prior to any deposit being required. Airline baggage fees may apply. Please review all terms and conditions before booking.